Perinatal Hypoxic and Ischemic Damage to the Central Nervous System Causes Changes in the Expression of Connexin 43 and CD38 and ADP-Ribosyl Cyclase Activity in Brain Cells

被引：0
|
作者：
A. B. Salmina
N. A. Malinovskaya
O. S. Okuneva
T. E. Taranushenko
A. A. Fursov
S. V. Mikhutkina
A. V. Morgun
S. V. Prokopenko
L. D. Zykova
机构：
[1] Krasnoyarsk State Medical Agency,Department of Biochemistry with Courses of Medical, Pharmaceutical, and Toxicological Chemistry
[2] Federal Agency for Public Health and Social Development,Department of Childhood Diseases No. 1
[3] Krasnoyarsk State Medical Agency,Institute of Molecular Medicine and Pathological Biochemistry
[4] Federal Agency for Public Health and Social Development,Department of Nervous Diseases
[5] Krasnoyarsk State Medical Agency,Department of Pathological Anatomy
[6] Federal Agency for Public Health and Social Development,undefined
[7] Krasnoyarsk State Medical Agency,undefined
[8] Federal Agency for Public Health and Social Development,undefined
[9] Krasnoyarsk State Medical Agency,undefined
[10] Federal Agency for Public Health and Social Development,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2008年 / 146卷
关键词：
brain; perinatal hypoxia/ischemia; CD38; connexin 43;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The expression of connexin 43 and CD38 and ADP ribosyl cyclase activity in brain cells were studied in rats with experimental hypoxic and ischemic damage to the CNS. Changes in the expression and activity of the enzyme were detected over the course of ischemic injury indicating a possible contribution of NAD+-converting activity and NAD+-transporting processes to the pathogenesis of acute cerebral ischemic injury.
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页码：733 / 736
页数：3
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