TGFβ signaling in health and disease

被引:0
|
作者
Rosemary J Akhurst
机构
[1] the Mt. Zion Cancer Research Institute,
[2] University of California,undefined
来源
Nature Genetics | 2004年 / 36卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Inactivating mutations in TGFBR2, encoding the transforming growth factor-β (TGFβ) type 2 receptor, may account for up to 10% of cases of Marfan syndrome. This finding has implications for a wider spectrum of disorders, including cancer, fibrosis and inflammatory and cardiovascular diseases, which are influenced by TGFβ.
引用
收藏
页码:790 / 792
页数:2
相关论文
共 50 条
  • [1] TGFβ signaling in health and disease
    Akhurst, RJ
    NATURE GENETICS, 2004, 36 (08) : 790 - 792
  • [2] Correction: Corrigendum: TGFβ signaling in health and disease
    R J Akhurst
    Nature Genetics, 2004, 36 (9) : 1024 - 1024
  • [3] TGF-β signaling in health, disease, and therapeutics
    Deng, Ziqin
    Fan, Tao
    Xiao, Chu
    Tian, He
    Zheng, Yujia
    Li, Chunxiang
    He, Jie
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 9 (01)
  • [4] TGFβ signaling pathways in human health and disease
    Chen, Pei-Yu
    Qin, Lingfeng
    Simons, Michael
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 10
  • [5] TGF-β Signaling in Lung Health and Disease
    Saito, Akira
    Horie, Masafumi
    Nagase, Takahide
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (08)
  • [6] TGF-j3 signaling in health and disease
    Massague, Joan
    Sheppard, Dean
    CELL, 2023, 186 (19) : 4007 - 4037
  • [7] TGF-β signaling in intervertebral disc health and disease
    Chen, S.
    Liu, S.
    Ma, K.
    Zhao, L.
    Lin, H.
    Shao, Z.
    OSTEOARTHRITIS AND CARTILAGE, 2019, 27 (08) : 1109 - 1117
  • [8] TGFβ signaling in health and disease (vol 36, pg 790, 2004)
    Akhurst, RJ
    NATURE GENETICS, 2004, 36 (09) : 1024 - 1024
  • [9] TGF-β signaling in renal disease
    Böttinger, EP
    Bitzer, M
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2002, 13 (10): : 2600 - 2610
  • [10] Mutations of TGFβ signaling molecules in human disease
    Harradine, Kelly A.
    Akhurst, Rosemary J.
    ANNALS OF MEDICINE, 2006, 38 (06) : 403 - 414