The super elongation complex (SEC) family in transcriptional control

被引：0
|
作者：
Zhuojuan Luo
Chengqi Lin
Ali Shilatifard
机构：
[1] Zhuojuan Luo,
[2] Chengqi Lin and Ali Shilatifard are at the Stowers Institute for Medical Research,undefined
[3] 1000 East 50th Street,undefined
[4] Kansas City,undefined
[5] Missouri 64110,undefined
[6] USA.,undefined
来源：
Nature Reviews Molecular Cell Biology | 2012年 / 13卷
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摘要：
The super elongation complex (SEC) consists of the RNA polymerase II (Pol II) elongation factors eleven-nineteen Lys-rich leukaemia (ELL) proteins, positive transcription elongation factor b (P-TEFb) and several frequent mixed lineage leukaemia (MLL) translocation partners. The SEC controls transcription elongation in the presence or absence of promoter-proximal paused Pol II, and its gene target specificity depends on protein components forming distinct SEC complexes.
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页码：543 / 547
页数：4
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