A-optimal designs for treatment-control comparisons in microarray experiments with random block effects

被引：0

作者：

Kunert J. ^{[1
]}

Mersmann S. ^{[1
]}

机构：

[1] Department of Statistics, TU Dortmund University

来源：

Journal of Statistical Theory and Practice | 2011年 / 5卷 / 1期

关键词：

A-optimality; Control treatment; Information matrix; Mixed model; Simple block model; Test treatments;

D O I：

10.1080/15598608.2011.10412051

中图分类号：

学科分类号：

摘要：

Designs for two colour microarrays can be considered as block designs with block size two. The paper considers a model where the block effects are random and determines a lower bound for the A-criterion of any design for the comparison of v treatments with a control. Only in rare cases there will be a design which attains the bound, but it can be used to calculate the efficiency of good designs. © Grace Scientific Publishing, LLC.

引用

页码：69 / 79

页数：10

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