H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

被引：0

作者：

Giulia Saredi

Hongda Huang

Colin M. Hammond

Constance Alabert

Simon Bekker-Jensen

Ignasi Forne

Nazaret Reverón-Gómez

Benjamin M. Foster

Lucie Mlejnkova

Till Bartke

Petr Cejka

Niels Mailand

Axel Imhof

Dinshaw J. Patel

Anja Groth

机构：

[1] Biotech Research and Innovation Centre (BRIC) and Centre for Epigenetics,Department of Molecular Biology

[2] Faculty of Health and Medical Sciences,undefined

[3] University of Copenhagen,undefined

[4] Structural Biology Program,undefined

[5] Memorial Sloan-Kettering Cancer Center,undefined

[6] The Novo Nordisk Foundation Center for Protein Research,undefined

[7] University of Copenhagen,undefined

[8] Biomedical Center and Center for Integrated Protein Science Munich,undefined

[9] Ludwig-Maximilians University,undefined

[10] MRC Clinical Sciences Centre (CSC) and Institute of Clinical Sciences (ICS),undefined

[11] Faculty of Medicine,undefined

[12] Imperial College London,undefined

[13] Institute of Molecular Cancer Research,undefined

[14] University of Zurich,undefined

来源：

Nature | 2016年 / 534卷

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摘要：

We have a limited understanding of how cells mark and identify newly replicated genomic loci that have a sister chromatid; here, unmethylated K20 in the tail of new histone H4 is shown to serve as a signature of post-replicative chromatin, which is specifically recognized by the homologous recombination complex TONSL–MMS22L.

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页码：714 / 718

页数：4

共 6 条

[1] H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex
Saredi, Giulia
Huang, Hongda
Hammond, Colin M.
Alabert, Constance
Bekker-Jensen, Simon
Forne, Ignasi
Reveron-Gomez, Nazaret
Foster, Benjamin M.
Mlejnkova, Lucie
Bartke, Till
Cejka, Petr
Mailand, Niels
Imhof, Axel
Patel, Dinshaw J.
Groth, Anja
NATURE, 2016, 534 (7609) : 714 - +
[2] THE TONSL-MMS22L DNA REPAIR COMPLEX IS A H4K20me0 READER
不详
CANCER DISCOVERY, 2016, 6 (08) : 816 - 816
[3] H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2
Simonetta, Marco
de Krijger, Inge
Serrat, Judit
Moatti, Nathalie
Fortunato, Diogo
Hoekman, Liesbeth
Bleijerveld, Onno B.
Altelaar, A. F. Maarten
Jacobs, Jacqueline J. L.
CELL CYCLE, 2018, 17 (01) : 124 - 136
[4] DICER- and MMSET-catalyzed H4K20me2 recruits the nucleotide excision repair factor XPA to DNA damage sites
Chitale, Shalaka
Richly, Holger
JOURNAL OF CELL BIOLOGY, 2018, 217 (02): : 527 - 540
[5] Both combinatorial K4me0-K36me3 marks on sister histone H3s of a nucleosome are required for Dnmt3a-Dnmt3L mediated de novo DNA methylation
Gong, Ting
Gu, Xin
Liu, Yu-Ting
Zhou, Zhen
Zhang, Ling-Li
Wen, Yang
Zhong, Wei-Li
Xu, Guo-Liang
Zhou, Jin-Qiu
JOURNAL OF GENETICS AND GENOMICS, 2020, 47 (02) : 105 - 114
[6] Both combinatorial K4me0-K36me3 marks on sister histone H3s of a nucleosome are required for Dnmt3a-Dnmt3L mediated de novo DNA methylation
Ting Gong
Xin Gu
Yu-Ting Liu
Zhen Zhou
Ling-Li Zhang
Yang Wen
Wei-Li Zhong
Guo-Liang Xu
Jin-Qiu Zhou
Journal of Genetics and Genomics, 2020, 47 (02) : 105 - 114

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