Label-free quantitative detection using porous silicon as optical biosensor

被引：0
|
作者：
Fu-ru Zhong
Xiao-lin Ma
Xiao-yi Lü
Zhen-hong Jia
机构：
[1] Xinjiang University,School of Chemistry and Chemical Engineering
[2] Xinjiang University,College of Life Sciences and Technology
[3] Xinjiang University,College of Information Science and Engineering
来源：
Optoelectronics Letters | 2012年 / 8卷 / 4期
关键词：
Raman Spectrum; Porous Silicon; Raman Intensity; Porous Silicon Layer; Porous Silicon Sample;
D O I：
10.1007/s11801-012-2244-3
中图分类号：
学科分类号：
摘要：
The single-layer porous silicon is prepared by electrochemistry etching method, which is used as an immunosensor for determining recombinant mouse zona pellucida 3 fusion protein (r-mZP3) by Raman spectroscopy analysis at room temperature. The molecule binding increases the effective optical thickness (EOT), and thus the Raman spectrum intensity decreases. The concentration and variation of Raman intensity show a good linear quantitative relation. The excellent sensing performance could open the way to a new family of optical sensors for biological standardization.
引用
收藏
页码：314 / 317
页数：3
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