Folate Fortification and Survival of Children with Acute Lymphoblastic Leukemia

被引：0
|
作者：
Deborah A. Kennedy
Sandy Grupp
Mark Greenberg
Gideon Koren
机构：
[1] The Hospital for Sick Children,The Motherisk Program
[2] University of Toronto,Leslie Dan Faculty of Pharmacy
[3] Pediatric Oncology Group of Ontario (POGO),Department of Pediatrics, Faculty of Medicine
[4] University of Toronto,Division of Clinical Pharmacology/Toxicology
[5] Hospital for Sick Children,undefined
来源：
Pediatric Drugs | 2011年 / 13卷
关键词：
Folate; Acute Lymphoblastic Leukemia; Bone Marrow Transplant; Spina Bifida; Neural Tube Defect;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: The antifolate drug methotrexate is a mainstay of treatment for children diagnosed with acute lymphoblastic leukemia (ALL). There have been concerns regarding the impact of folate fortification on the efficacy of methotrexate therapy and hence treatment outcomes of ALL.
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页码：193 / 196
页数：3
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