Synthesis of New Tetrazole Derivatives and Their Biological Evaluation

被引:0
|
作者
H. A. Soliman
A. Kalmouch
H. M. Awad
N. A. M. Abdel Wahed
机构
[1] National Research Centre,Photochemistry Department
[2] National Research Centre,Peptide Chemistry Department
[3] National Research Centre,Tanning Materials and Leather Technology Department
[4] National Research Centre,Chemistry of Natural and Microbial Products Department
来源
关键词
tetrachlorosilane; 1,5-disubstituted tetrazoles; mild conditions; anticancer activity; anti-microbial activity;
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摘要
An operationally simple and efficient method of synthesis of novel 1,5-disubstituted tetrazoles with high yields from easily accessible 2-(2-benzamido-3-arylacrylamido)acetate under mild conditions is developed. Anticancer and anti-microbial tests of the new tetrazole derivatives have been carried out.
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页码:1726 / 1733
页数:7
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