Severe insulin resistance contrasting with mild anthropometric changes in the adipose tissue of HIV-infected children with lipohypertrophy

被引:0
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作者
M Beregszàszi
D Jaquet
M Lévine
E Ortega-Rodriguez
V Baltakse
M Polak
C Lévy-Marchal
机构
[1] INSERM Unit 457,Department of Immuno
[2] Robert Debré Hospital,Hematology
[3] Robert Debré Hospital,undefined
[4] Pediatric Clinic,undefined
[5] Robert Debré Hospital,undefined
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关键词
lipodystrophy; HIV-infection; microdialysis; insulin resistance; children;
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摘要
BACKGROUND: The HIV-associated lipodystrophic syndrome (HIV-LDS) combines redistribution of fat mass with insulin resistance and hyperlipidemia. We have previously reported that HIV-LDS prevails in children in a comparable pattern as in adults. The metabolic activity itself of the lipodystrophic adipose tissue in HIV infection has been poorly studied.
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页码:25 / 30
页数:5
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