Smads keep TABs on inflammation

被引：0

作者：

Rashu B Seth

Zhijian J Chen

机构：

[1] University of Texas Southwestern Medical Center,Rashu B. Seth and Zhijian J. Chen are with the Howard Hughes Medical Institute and Department of Molecular Biology

[2] Dallas,undefined

[3] Texas 75390,undefined

[4] USA. zhijian.chen@utsouthwestern.edu,undefined

来源：

Nature Immunology | 2007年 / 8卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Smad7 controls inflammation by negatively regulating activation of the transcription factor NF-κB. New work shows that Smad7 inhibits NF-κB by binding to the regulatory proteins TAB2 and TAB3, thereby blocking association of the E3 ubiquitin ligase TRAF2 with the kinase TAK1.

引用

页码：477 / 478

页数：1

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[1] Smads keep TABs on inflammation
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Chen, Zhijian J.
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