Molecular mechanisms of sex determination and gonadal sex differentiation in fish

被引：0
|
作者：
Y. Nagahama
机构：
[1] National Institute for Basic Biology,Laboratory of Reproductive Biology, Department of Developmental Biology
[2] CREST,undefined
来源：
Fish Physiology and Biochemistry | 2005年 / 31卷
关键词：
Fish; Sex-determining gene; Estrogen; DMRT1; Gonadal sex differentiation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We have used various genetic and molecular approaches to investigate the mechanisms of sex determination and gonadal sex differentiation in fish. DMY was identified as the sex-determining gene of medaka. In tilapia, endogenous estrogens act as natural inducers of ovarian differentiation, while DMRT1 may be important for testicular differentiation. The roles of these regulators in sex determination and gonadal sex differentiation were ascertained using a gene or hormonal blockade strategy.
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页码：105 / 109
页数：4
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