Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N

被引:0
|
作者
Christopher W. Carroll
Mariana C.C. Silva
Kristina M. Godek
Lars E.T. Jansen
Aaron F. Straight
机构
[1] Stanford University School of Medicine,Department of Biochemistry
[2] Beckman Center,Department of Biochemistry
[3] Laboratory for Epigenetic Mechanisms,undefined
[4] Instituto Gulbenkian de Ciência,undefined
[5] Rua da Quinta Grande,undefined
[6] 6,undefined
[7] Stanford University School of Medicine,undefined
[8] Beckman Center,undefined
来源
Nature Cell Biology | 2009年 / 11卷
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摘要
The histone H3 variant CENP-A specifies centromere identity. CENP-N is the first selective binding partner of CENP-A. Inhibition of CENP-N binding to CENP-A or CENP-N depletion prevents the recruitment of the other CENP proteins involved in centromere assembly.
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页码:896 / 902
页数:6
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