Depleting senescent cells to combat aging

被引:0
|
作者
Hartmut Geiger
机构
[1] Hartmut Geiger is at the Institute for Molecular Medicine and Aging Research Center Ulm,and in the Division of Experimental Hematology and Cancer Biology
[2] University of Ulm,undefined
[3] Ulm,undefined
[4] Germany,undefined
[5] Cincinnati Children's Hospital Medical Center,undefined
[6] Cincinnati,undefined
[7] Ohio,undefined
[8] USA.,undefined
来源
Nature Medicine | 2016年 / 22卷
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摘要
A new study in mice suggests that pharmacologically targeting the apoptosis proteins BCL-2 and BCL-xL can clear senescent cells from bone marrow and ameliorate stem cell function during aging, bringing us a step closer to preventing senescence-associated tissue attrition in the clinic.
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页码:23 / 24
页数:1
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