Vemurafenib in Chinese patients with BRAFV600 mutation–positive unresectable or metastatic melanoma: an open-label, multicenter phase I study

被引：0
|
作者：
Lu Si
Xiaoshi Zhang
Zhen Xu
Qiudi Jiang
Lilian Bu
Xuan Wang
Lili Mao
Weijiang Zhang
Nicole Richie
Jun Guo
机构：
[1] Peking University Cancer Hospital & Institute,Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education)
[2] Sun Yat-sen University Cancer Center,undefined
[3] Roche Product Development in Asia Pacific,undefined
[4] Roche R&D Center China Ltd.,undefined
[5] Roche Innovation Center New York,undefined
[6] Genentech,undefined
[7] Inc.,undefined
来源：
BMC Cancer | / 18卷
关键词：
-positive; Advanced melanoma; Vemurafenib; China; Asia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Vemurafenib in Chinese patients with BRAFV600 mutation-positive unresectable or metastatic melanoma: an open-label, multicenter phase I study
    Si, Lu
    Zhang, Xiaoshi
    Xu, Zhen
    Jiang, Qiudi
    Bu, Lilian
    Wang, Xuan
    Mao, Lili
    Zhang, Weijiang
    Richie, Nicole
    Guo, Jun
    BMC CANCER, 2018, 18
  • [2] Open-label, multicenter safety study of vemurafenib in patients with BRAFV600 mutation-positive metastatic melanoma
    Larkin, James M. G.
    Del Vecchio, Michele
    Ascierto, Paolo Antonio
    Schachter, Jacob
    Garbe, Claus
    Neyns, Bart
    Mandala, Mario
    Lorigan, Paul
    Miller, Wilson H.
    Guminski, Alexander David
    Berking, Carola
    Rutkowski, Piotr
    Queirolo, Paola
    Hauschild, Axel
    Arance, Ana Maria
    Brown, Michael Paul
    Mitchell, Lada
    Veronese, Maria Luisa
    Blank, Christian U.
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [3] Vemurafenib in patients with BRAFV600 mutated metastatic melanoma: an open-label, multicentre, safety study
    Larkin, James
    Del Vecchio, Michele
    Ascierto, Paolo A.
    Krajsova, Ivana
    Schachter, Jacob
    Neyns, Bart
    Espinosa, Enrique
    Garbe, Claus
    Sileni, Vanna Chiarion
    Gogas, Helen
    Miller, Wilson H., Jr.
    Mandala, Mario
    Hospers, Geke A. P.
    Arance, Ana
    Queirolo, Paola
    Hauschild, Axel
    Brown, Michael P.
    Mitchell, Lada
    Veronese, Luisa
    Blank, Christian U.
    LANCET ONCOLOGY, 2014, 15 (04): : 436 - 444
  • [4] Cobimetinib Plus Vemurafenib: A Review in BRAFV600 Mutation-Positive Unresectable or Metastatic Melanoma
    Keating, Gillian M.
    DRUGS, 2016, 76 (05) : 605 - 615
  • [5] Cobimetinib Plus Vemurafenib: A Review in BRAFV600 Mutation-Positive Unresectable or Metastatic Melanoma
    Gillian M. Keating
    Drugs, 2016, 76 : 605 - 615
  • [6] Phase I/II study of vemurafenib in patients with unresectable or recurrent melanoma with BRAFV600 mutations
    Yamazaki, Naoya
    Kiyohara, Yoshio
    Sugaya, Naofumi
    Uhara, Hisashi
    JOURNAL OF DERMATOLOGY, 2015, 42 (07): : 661 - 666
  • [7] Vemurafenib in patients with BRAFV600 mutation-positive melanoma with symptomatic brain metastases: Final results of an open-label pilot study
    Dummer, Reinhard
    Goldinger, Simone M.
    Turtschi, Christian P.
    Eggmann, Nina B.
    Michielin, Olivier
    Mitchell, Lada
    Veronese, Luisa
    Hilfiker, Paul Rene
    Felderer, Lea
    Rinderknecht, Jeannine D.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 (03) : 611 - 621
  • [8] A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAFV600E mutation-positive metastatic melanoma
    J. F. Grippo
    W. Zhang
    D. Heinzmann
    K. H. Yang
    J. Wong
    A. K. Joe
    P. Munster
    N. Sarapa
    A. Daud
    Cancer Chemotherapy and Pharmacology, 2014, 73 : 103 - 111
  • [9] BRAFV600 mutation levels and response to vemurafenib in metastatic melanoma.
    Lebbe, Celeste
    Howkit, Alexandre
    Sadoux, Aurelie
    Podgorniak, Marie Pierre
    Battistella, Maxime
    Pages, Cecile
    Roux, Jennifer
    Porcher, Raphael
    Tost, Jorg
    Mourah, Samia
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [10] BRAFV600 mutation levels predict response to vemurafenib in metastatic melanoma
    Lebbe, Celeste
    How-Kit, Alexandre
    Battistella, Maxime
    Sadoux, Aurelie
    Podgorniak, Marie-Pierre
    Sidina, Irina
    Pages, Cecile
    Roux, Jennifer
    Porcher, Raphael
    Tost, Jorg
    Mourah, Samia
    MELANOMA RESEARCH, 2014, 24 (04) : 415 - 418
12345