Hydroxyapatite-Chitosan Bombyx mori: Synthesis and Physicochemical Properties

Composites of chitosan Bombyx mori with hydroxyapatite – (Ca10(PO4)6(OH)2) were obtained and their interaction in aqueous solutions was studied. The composition and structure of composites obtained at various mass ratios were studied. The possibility of controlling the composition and morphology of composites by varying the ratios of the initial reagents was shown. FITR and UV spectroscopic methods were used to investigate the structure of composites. The results of XRDA studies have shown that depending on the CS/HA ratio, CS/HA crystals with sizes from 6.9 to 20.4 nm were formed in the system. Using the methods of potentiometry, conductometry and viscometric measurements the equivalent composition of the composite was determined, which is CS/HA-70:30 mass %. It was found that nanostructured composites with minimum sizes from 2 to 15 nm were obtained under the selected synthesis conditions. The obtained data are applied interest for the prevention and treatment of osteomolyosis, osteoporosis and bone replacement of living organisms.