Application of 3D bioprinting in the prevention and the therapy for human diseases

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作者
Hee-Gyeong Yi
Hyeonji Kim
Junyoung Kwon
Yeong-Jin Choi
Jinah Jang
Dong-Woo Cho
机构
[1] Chonnam National University,Department of Rural and Biosystems Engineering, College of Agriculture and Life Sciences
[2] Pohang University of Science and Technology (POSTECH),Department of Mechanical Engineering
[3] Korea Institute of Materials Science (KIMS),Department of Advanced Biomaterials Research
[4] POSTECH,Department of Convergence IT Engineering
[5] Yonsei University,Institute of Convergence Science
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摘要
Rapid development of vaccines and therapeutics is necessary to tackle the emergence of new pathogens and infectious diseases. To speed up the drug discovery process, the conventional development pipeline can be retooled by introducing advanced in vitro models as alternatives to conventional infectious disease models and by employing advanced technology for the production of medicine and cell/drug delivery systems. In this regard, layer-by-layer construction with a 3D bioprinting system or other technologies provides a beneficial method for developing highly biomimetic and reliable in vitro models for infectious disease research. In addition, the high flexibility and versatility of 3D bioprinting offer advantages in the effective production of vaccines, therapeutics, and relevant delivery systems. Herein, we discuss the potential of 3D bioprinting technologies for the control of infectious diseases. We also suggest that 3D bioprinting in infectious disease research and drug development could be a significant platform technology for the rapid and automated production of tissue/organ models and medicines in the near future.
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