Simultaneous determination of dopamine and serotonin using a carbon nanotubes-ionic liquid gel modified glassy carbon electrode

被引：0
|
作者：
Yongxiang Sun
Junjie Fei
Jie Hou
Qin Zhang
Yanling Liu
Benan Hu
机构：
[1] Xiangtan University,College of Chemistry
[2] Xiangtan University,Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education
来源：
Microchimica Acta | 2009年 / 165卷
关键词：
Ionic liquid; Carbon nanotube; Dopamine; Serotonin; Chemically modified electrode;
D O I：
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中图分类号：
学科分类号：
摘要：
An electrochemical sensor based on carbon nanotubes (CNTs)-ionic liquid (IL) composite has been developed for the simultaneous determination of serotonin (5-HT) and dopamine (DA). The CNTs-IL composite modified electrode presents excellent selectivity and sensitivity towards 5-HT and DA and eliminates the interference of ascorbic acid. The parameters which influence the determination of 5-HT and DA have been investigated. Under optimized conditions, linear calibration graphs were obtained in the range from 20 nM to 7 µM, with a detection of limit of 8 nM, for 5-HT, and in the range from 0.1 to 12 µM, with a detection of limit of 60 nM, for DA. The electrode has been applied to the assay of 5-HT and DA in human blood serum with good results.
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页码：373 / 379
页数：6
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