Regulatory roles of mast cells in immune responses

被引：0
|
作者：
Hideaki Morita
Hirohisa Saito
Kenji Matsumoto
Susumu Nakae
机构：
[1] National Research Institute for Child Health and Development,Department of Allergy and Clinical Immunology
[2] University of Zurich,Swiss Institute of Allergy and Asthma Research
[3] The University of Tokyo,Laboratory of Systems Biology, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science
[4] Japan Science and Technology Agency,Precursory Research for Embryonic Science and Technology (PRESTO)
来源：
Seminars in Immunopathology | 2016年 / 38卷
关键词：
Mast cell; Rejection; Graft-versus-host disease; Contact hypersensitivity; Innate-type allergic airway inflammation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Mast cells are important immune cells for host defense through activation of innate immunity (via toll-like receptors or complement receptors) and acquired immunity (via FcεRI). Conversely, mast cells also act as effector cells that exacerbate development of allergic or autoimmune disorders. Yet, several lines of evidence show that mast cells act as regulatory cells to suppress certain inflammatory diseases. Here, we review the mechanisms by which mast cells suppress diseases.
引用
收藏
页码：623 / 629
页数：6
相关论文
共 50 条
  • [1] Regulatory roles of mast cells in immune responses
    Morita, Hideaki
    Saito, Hirohisa
    Matsumoto, Kenji
    Nakae, Susumu
    [J]. SEMINARS IN IMMUNOPATHOLOGY, 2016, 38 (05) : 623 - 629
  • [2] Mast cells - key effector cells in immune responses
    Metz, Martin
    Maurer, Marcus
    [J]. TRENDS IN IMMUNOLOGY, 2007, 28 (05) : 234 - 241
  • [3] Effector and potential immunoregulatory roles of mast cells in IgE-associated acquired immune responses
    Grimbaldeston, Michele A.
    Metz, Martin
    Yu, Mang
    Tsai, Mindy
    Galli, Stephen J.
    [J]. CURRENT OPINION IN IMMUNOLOGY, 2006, 18 (06) : 751 - 760
  • [4] New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development
    Yosuke Kurashima
    Hiroshi Kiyono
    [J]. Experimental & Molecular Medicine, 2014, 46 : e83 - e83
  • [5] New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development
    Kurashima, Yosuke
    Kiyono, Hiroshi
    [J]. EXPERIMENTAL AND MOLECULAR MEDICINE, 2014, 46 : e83 - e83
  • [6] Mast cells and basophils in cutaneous immune responses
    Otsuka, A.
    Kabashima, K.
    [J]. ALLERGY, 2015, 70 (02) : 131 - 140
  • [7] Mast cells in the development of adaptive immune responses
    Galli, SJ
    Nakae, S
    Tsai, M
    [J]. NATURE IMMUNOLOGY, 2005, 6 (02) : 135 - 142
  • [8] Mast cells in the development of adaptive immune responses
    Stephen J Galli
    Susumu Nakae
    Mindy Tsai
    [J]. Nature Immunology, 2005, 6 : 135 - 142
  • [9] Responses of Mast Cells to Pathogens: Beneficial and Detrimental Roles
    Jimenez, Mariela
    Cervantes-Garcia, Daniel
    Cordova-Davalos, Laura E.
    Perez-Rodriguez, Marian Jesabel
    Gonzalez-Espinosa, Claudia
    Salinas, Eva
    [J]. FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [10] Roles of Immune Cells and Mechanisms of Immune Responses in Periodontitis
    Xu, Xiao Wei
    Liu, Xia
    Shi, Ce
    Sun, Hong Chen
    [J]. CHINESE JOURNAL OF DENTAL RESEARCH, 2021, 24 (04): : 219 - 230
12345