Climate change has been considered among the greatest challenge to living organisms. Medicinal and aromatic plants are no exception to it. The practice of use of therapeutic plant has proved to be particularly important in the health system all over the world. WHO predicted that 60% of the earth population and 80% of the population of 3rd world countries bank on herbal medicine, for their wellbeing requirements. Environmental conditions under the influence of climate change is dreadful not only for declining the quality of planting material but also severely retards public health. Our main idea is to focus on cultivation of local valued plants, training for farmers, preservation of traditional knowledge, developing awareness among people regarding alarming influence of climate change on medicinal plants. Anthropogenic activity-mediated climate change has devastating impacts on species varieties, on the earth. The augmented releases of greenhouse gases in the air; mainly of CO2 is the main reason for climatic changes. Study reveals the true understanding of effect of changing climate scenario on Medicinal plants. Differential patterns of climate change cause abiotic stress and can change the growth physiology, growth pattern, declines in biomass production, changes in phytochemical active constituents and overall changes the quality and safety of medicinal plants.After studying enormous review papers, detailed information regarding repercussions of climate change on therapeutic plants is found to be so negligible as compared to other trade crops, therefore we have tried to highlight the discipline in a comprehensive manner.