Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped

被引：0
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作者：
Mohammad Tariq
Arnaldo H. de Souza
Mohammed Bensellam
Heeyoung Chae
Manon Jaffredo
Anne-Françoise Close
Jean-Philippe Deglasse
Laila R. B. Santos
Antoine Buemi
Nizar I. Mourad
Anne Wojtusciszyn
Matthieu Raoux
Patrick Gilon
Christophe Broca
Jean-Christophe Jonas
机构：
[1] Université catholique de Louvain,Secteur des sciences de la santé, Institut de recherche expérimentale et clinique, Pôle d’endocrinologie, diabète et nutrition
[2] Lund University,Lund University Diabetes Centre, Department of Clinical Sciences
[3] University of Bordeaux,CNRS, Institute of Chemistry and Biology of Membranes and Nano
[4] Bio Base Europe Pilot Plant (BBEPP),objects, UMR 5248
[5] Université catholique de Louvain,Secteur des sciences de la santé, Institut de recherche expérimentale et clinique, Pôle de chirurgie expérimentale
[6] CHU Montpellier,Laboratoire de Thérapie Cellulaire du Diabète, Institut de Médecine Régénérative et Biothérapies, Hôpital St Eloi
[7] Centre Hospitalier Universitaire Vaudois and Université de Lausanne,Service d’Endocrinologie, Diabétologie et Métabolisme
来源：
Diabetologia | 2023年 / 66卷
关键词：
Cytosolic calcium; Glucose response curve; Glucotoxicity; Human islets; Long-term culture;
D O I：
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摘要：
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页码：709 / 723
页数：14
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