Purification of hematopoietic stem cells from bone marrow

被引:0
|
作者
Chen Tian
Yizhuo Zhang
机构
[1] Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy
来源
Annals of Hematology | 2016年 / 95卷
关键词
Hematopoietic stem cell; Markers; Purification; Flow cytometry;
D O I
暂无
中图分类号
学科分类号
摘要
Lifelong production of blood cells is sustained by hematopoietic stem cells (HSC) which reside at a very low frequency within the bone marrow (BM). The use of flow cytometry has been critical in establishing methods to isolate and characterize HSCs and their progenitors. For more than 30 years, researchers have uncovered many novel markers that when used in combination significantly enhance the purification of HSCs from murine and human bone marrow. Here, we review the phenotypic markers and strategies used to purify HSCs.
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页码:543 / 547
页数:4
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