A Nonpeptide, Piperidine Renin Inhibitor Provides Renal and Cardiac Protection in Double-Transgenic Mice Expressing Human Renin and Angiotensinogen Genes

被引：0
|
作者：
Terry C. Major
Bronia Olszewski
Wendy Rosebury
Carlin Okerberg
Tage Carlson
Robert Ostroski
Richard Schroeder
Mark C. Kowala
Robert Leadley
机构：
[1] Pfizer Global Research & Development,Cardiovascular and Atherosclerosis Biology
[2] Pfizer,Drug Safety Research and Development
[3] Inc.,Robert Bartlett Extracorporeal Life Support Laboratory, Department of General Surgery
[4] Pfizer Global Research & Development,undefined
[5] Pfizer,undefined
[6] Inc.,undefined
[7] University of Michigan Health System,undefined
来源：
Cardiovascular Drugs and Therapy | 2008年 / 22卷
关键词：
Cardioprotection; Renoprotection; Hypertensive Double Transgenic Mice; Enalapril; Candesartan; Renin Inhibitor; Left Ventricular Hypertrophy and Microalbuminuria;
D O I：
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学科分类号：
摘要：
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页码：469 / 478
页数：9
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