Primitive neuroectodermal tumor (PNET) of the lung in an adult woman

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作者
Mariam Gachechiladze
Josef Škarda
Maha Ibrahim
Tomáš Tichý
Patrik Flodr
Pavla Latálová
Jiří Ehrmann
Radek Trojanec
Zdenek Kolář
机构
[1] Faculty of Medicine and Dentistry,Department of Clinical and Molecular Pathology and Institute of Molecular and Translational Medicine (IMTM)
[2] Palacky University,undefined
[3] School of Cancer Sciences,undefined
[4] The University of Birmingham,undefined
关键词
Primitive neuroectodermal tumor; Ewing’s sarcoma; Lung; Differential diagnosis;
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摘要
Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed.
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