Nutrition during childhood and adolescence is an important
determinant of development and health, both for the child and
the later adult. In industrialised countries as well as in many
countries of economic transition, emphasis has moved from
combating nutrient deficiencies to research on the effects of
overnutrition and food selection. Prevention of chronic diseases
including obesity have become a major focus in research.
However, the complex relation between infant growth and its
related endocrine and metabolic changes on the one hand and the
influence of nutrition and nutritional status on the other hand
still need to be understood in detail. Studies aiming to
elucidate this have to follow children and adolescents during
their growth period. The following pages display the features of
the German DONALD Study (DOrtmund Nutritional and Anthropometric Longitudinally Designed Study) which was specifically
designed to address these complex research questions. Finally,
comparisons to other studies are made and the specific strength
and weaknesses of this study are discussed. As the DONALD study
offers unique research opportunities and due to its long
follow-up an abundance of data, collaborative research is
encouraged.
机构:National Institutes of Health,Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Malignancies Branch, Center for Cancer Research, National Cancer Institute
Charalampos S. Floudas
Gagandeep Brar
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机构:National Institutes of Health,Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Malignancies Branch, Center for Cancer Research, National Cancer Institute
Gagandeep Brar
Tim F. Greten
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机构:National Institutes of Health,Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Malignancies Branch, Center for Cancer Research, National Cancer Institute
Tim F. Greten
Digestive Diseases and Sciences,
2019,
64
: 1030
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1040