Examination of multiple UGT1A and DPYD polymorphisms has limited ability to predict the toxicity and efficacy of metastatic colorectal cancer treated with irinotecan-based chemotherapy: a retrospective analysis

被引：0
|
作者：
Dan Liu
Jian Li
Jing Gao
Yanyan Li
Rui Yang
Lin Shen
机构：
[1] Peking University Cancer Hospital & Institute,Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Oncology
来源：
BMC Cancer | / 17卷
关键词：
Irinotecan; polymorphisms; polymorphisms; Metastatic colorectal cancer; Toxicity; Clinical response;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 30 条
  • [1] Examination of multiple UGT1A and DPYD polymorphisms has limited ability to predict the toxicity and efficacy of metastatic colorectal cancer treated with irinotecan-based chemotherapy: a retrospective analysis
    Liu, Dan
    Li, Jian
    Gao, Jing
    Li, Yanyan
    Yang, Rui
    Shen, Lin
    BMC CANCER, 2017, 17
  • [2] UGT1A polymorphisms associated with worse outcome in colorectal cancer patients treated with irinotecan-based chemotherapy
    Yu, Qianqian
    Zhang, Tao
    Xie, Conghua
    Qiu, Hong
    Liu, Bo
    Huang, Liu
    Peng, Ping
    Feng, Jueping
    Chen, Jigui
    Zang, Aihua
    Yuan, Xianglin
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 82 (01) : 87 - 98
  • [3] UGT1A polymorphisms associated with worse outcome in colorectal cancer patients treated with irinotecan-based chemotherapy
    Qianqian Yu
    Tao Zhang
    Conghua Xie
    Hong Qiu
    Bo Liu
    Liu Huang
    Ping Peng
    Jueping Feng
    Jigui Chen
    Aihua Zang
    Xianglin Yuan
    Cancer Chemotherapy and Pharmacology, 2018, 82 : 87 - 98
  • [4] The comprehensive analysis of UGT1A genetic polymorphisms in patients with metastatic gastrointestinal cancer treated with irinotecan chemotherapy
    Tsujinaka, T.
    Satoh, T.
    Ura, T.
    Sasaki, Y.
    Yamazaki, K.
    Munakata, M.
    Yamada, Y.
    Ishizuka, N.
    Hyodo, I.
    Sakata, Y.
    EJC SUPPLEMENTS, 2009, 7 (02): : 144 - 144
  • [5] Impact of UGT1A1 genotype on the efficacy and safety of irinotecan-based chemotherapy in metastatic colorectal cancer
    Iwasa, Satoru
    Muro, Kei
    Morita, Satoshi
    Park, Young Suk
    Nakamura, Masato
    Kotaka, Masahito
    Nishina, Tomohiro
    Matsuoka, Hiroshi
    Ahn, Joong Bae
    Lee, Keun-Wook
    Hong, Yong Sang
    Han, Sae Won
    Cho, Sang-Hee
    Zhang, Dong-Sheng
    Fang, Wei-Jia
    Bai, Li
    Yuan, Xiang-Lin
    Yuan, Ying
    Yamada, Yasuhide
    Sakamoto, Junichi
    Kim, Tae Won
    CANCER SCIENCE, 2021, 112 (11) : 4669 - 4678
  • [6] Refining the UGT1A Haplotype Associated with Irinotecan-Induced Hematological Toxicity in Metastatic Colorectal Cancer Patients Treated with 5-Fluorouracil/Irinotecan-Based Regimens
    Levesque, Eric
    Belanger, Anne-Sophie
    Harvey, Mario
    Couture, Felix
    Jonker, Derek
    Innocenti, Federico
    Cecchin, Erica
    Toffoli, Giuseppe
    Guillemette, Chantal
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2013, 345 (01): : 95 - 101
  • [7] UGT1A1 gene polymorphism: Impact on toxicity and efficacy of irinotecan-based regimens in metastatic colorectal cancer
    Christoph Schulz
    Volker Heinemann
    Andreas Schalhorn
    Nikolas Moosmann
    Thomas Zwingers
    Stefan Boeck
    Clemens Giessen
    Hans-Joachim Stemmler
    World Journal of Gastroenterology, 2009, 15 (40) : 5058 - 5066
  • [8] UGT1A1 gene polymorphism: Impact on toxicity and efficacy of irinotecan-based regimens in metastatic colorectal cancer
    Schulz, Christoph
    Heinemann, Volker
    Schalhorn, Andreas
    Moosmann, Nikolas
    Zwingers, Thomas
    Boeck, Stefan
    Giessen, Clemens
    Stemmler, Hans-Joachim
    WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (40) : 5058 - 5066
  • [9] Relationship between UGT1A1*6/*28 gene polymorphisms and the efficacy and toxicity of irinotecan-based chemotherapy
    Bai, Yu
    Wu, Ai-wei
    Ma, Xu
    Liu, Ying
    Zhang, Yan-hua
    ONCOTARGETS AND THERAPY, 2017, 10 : 3071 - 3081
  • [10] UGT1A1 gene polymorphism is associated with toxicity and clinical efficacy of irinotecan-based chemotherapy in patients with advanced colorectal cancer
    Xu, Chunlei
    Tang, Xushan
    Qu, Yanli
    Keyoumu, Saifuding
    Zhou, Ning
    Tang, Yong
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2016, 78 (01) : 119 - 130
123