Citrinamides, New Potentiators of Antifungal Miconazole Activity, Produced by Penicillium sp. FKI-1938

被引：0
|
作者：
Takashi Fukuda
Yoko Hasegawa
Yasunari Sakabe
Hiroshi Tomoda
Satoshi Ōmura
机构：
[1] Kitasato Institute for Life Sciences & Graduate School of Infection Control Sciences,
[2] Kitasato University,undefined
[3] School of Pharmacy,undefined
[4] Kitasato University,undefined
来源：
The Journal of Antibiotics | 2008年 / 61卷
关键词：
citrinamide; miconazole potentiator; sp.; fungal metabolite;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two new aromatic alkaloids, designated citrinamides A and B, were isolated from the culture broth of penicillium sp. FKI–1938 by solvent extraction, silica gel column chromatography and HPLC. Their structures were elucidated by spectroscopic analysis, including NMR and amino acid analysis. Citrinamides A and B showed moderate potentiation of miconazole activity against Candida albicans.
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页码：550 / 555
页数：5
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