Sensing RNA virus infections

被引:0
|
作者
Christopher F Basler
Adolfo García-Sastre
机构
[1] Mount Sinai School of Medicine,the Department of Microbiology
来源
Nature Chemical Biology | 2007年 / 3卷
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摘要
RIG-I is an RNA helicase that senses viral infections and triggers innate and adaptive immune mechanisms. Recent studies have identified RNAs bearing 5′-triphosphates as ligands of RIG-I and have suggested a mechanism for how RIG-I distinguishes viral RNA from host RNA.
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页码:20 / 21
页数:1
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