The positive feedback loop of MAD2L1/TYK2/STAT3 induces progression in B-cell acute lymphoblastic leukaemia

被引：0
|
作者：
Liwen Zhu
Xinyu Li
Diandian Liu
Wenke Bai
Huaqing Yang
Qianyi Cheng
Luhong Xu
Jianpei Fang
机构：
[1] Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University,Department of Pediatrics
[2] Sun Yat-Sen Memorial Hospital,Guangdong Provincial Key Laboratory of Malignant Tumour Epigenetics and Gene Regulation
[3] Sun Yat-Sen University,undefined
来源：
Journal of Cancer Research and Clinical Oncology | 2023年 / 149卷
关键词：
MAD2L1; B-ALL; TYK2/STAT3; Proliferation; Metastasis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：6527 / 6540
页数：13
相关论文
共 50 条
  • [1] The positive feedback loop of MAD2L1/TYK2/STAT3 induces progression in B-cell acute lymphoblastic leukaemia
    Zhu, Liwen
    Li, Xinyu
    Liu, Diandian
    Bai, Wenke
    Yang, Huaqing
    Cheng, Qianyi
    Xu, Luhong
    Fang, Jianpei
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023, 149 (09) : 6527 - 6540
  • [2] TYK2 Variants in B-Acute Lymphoblastic Leukaemia
    Turrubiartes-Martinez, Edgar
    Bodega-Mayor, Irene
    Delgado-Wicke, Pablo
    Molina-Jimenez, Francisca
    Casique-Aguirre, Diana
    Gonzalez-Andrade, Martin
    Rapado, Inmaculada
    Camos, Mireia
    Diaz-de-Heredia, Cristina
    Barragan, Eva
    Ramirez-Orellana, Manuel
    Aguado, Beatriz
    Figuera, Angela
    Martinez-Lopez, Joaquin
    Fernandez-Ruiz, Elena
    GENES, 2020, 11 (12) : 1 - 16
  • [3] Characterisation of TYK2 inhibitors as potential T-cell acute lymphoblastic leukaemia therapeutics
    Reader, J.
    EUROPEAN JOURNAL OF CANCER, 2016, 69 : S22 - S23
  • [4] COLONY-STIMULATING FACTOR 1-INDUCED STAT1 AND STAT3 ACTIVATION IS ACCOMPANIED BY PHOSPHORYLATION OF TYK2 IN MACROPHAGES AND TYK2 AND JAK1 IN FIBROBLASTS
    NOVAK, U
    HARPUR, AG
    PARADISO, L
    KANAGASUNDARAM, V
    JAWOROWSKI, A
    WILKS, AF
    HAMILTON, JA
    BLOOD, 1995, 86 (08) : 2948 - 2956
  • [5] Interleukin 3 activates not only JAK2 and STAT5, but also Tyk2, STAT1, and STAT3
    Nagata, Y
    Todokoro, K
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 221 (03) : 785 - 789
  • [6] Pathway Dependence on the Tyrosine Kinase TYK2 and Its Mediator STAT1 In T-Cell Acute Lymphoblastic Leukemia
    Sanda, Takaomi
    Tyner, Jeffrey W.
    Gutierrez, Alejandro
    Ngo, Vu N.
    Moriggl, Richard
    Ahn, Yebin
    Glover, Jason M.
    Chang, Bill H.
    Willis, Stephanie G.
    Staudt, Louis M.
    Druker, Brian J.
    Look, A. Thomas
    BLOOD, 2010, 116 (21) : 1298 - 1298
  • [7] Persistent Activation of JAK/STAT Signaling Plays an Important Role inin VitroJaki Resistance in TYK2-rearranged B-Cell Acute Lymphoblastic Leukaemia
    Tavakoli, Paniz
    Eadie, Laura N.
    Heatley, Susan L.
    Bruning, John B.
    White, Deborah L.
    BLOOD, 2020, 136
  • [8] Activation of Tyk2 and Stat3 is required for the apoptotic actions of interferon-β in primary pro-B cells
    Gamero, Ana M.
    Potla, Ramesh
    Wegrzyn, Joanna
    Szelag, Magdelena
    Edling, Andrea E.
    Shimoda, Kazuya
    Link, Daniel C.
    Dulak, Jozef
    Baker, Darren P.
    Tanabe, Yoshinari
    Grayson, Jason M.
    Larner, Andrew C.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (24) : 16238 - 16244
  • [9] The advances of E2A-PBX1 fusion in B-cell acute lymphoblastic Leukaemia
    Yang, Mengting
    Tang, Yanhui
    Zhu, Peng
    Lu, Haiquan
    Wan, Xiaohong
    Guo, Qulian
    Xiao, Lan
    Liu, Chunyan
    Guo, Ling
    Liu, Wenjun
    Yang, You
    ANNALS OF HEMATOLOGY, 2024, 103 (09) : 3385 - 3398
  • [10] Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia
    Akahane, Koshi
    Li, Zhaodong
    Etchin, Julia
    Berezovskaya, Alla
    Gjini, Evisa
    Masse, Craig E.
    Miao, Wenyan
    Rocnik, Jennifer
    Kapeller, Rosana
    Greenwood, Jeremy R.
    Tiv, Hong
    Sanda, Takaomi
    Weinstock, David M.
    Look, A. Thomas
    BRITISH JOURNAL OF HAEMATOLOGY, 2017, 177 (02) : 271 - 282
12345