Dipeptidylpeptidase-4 Inhibitors (Gliptins)Focus on Drug-Drug Interactions

被引:0
|
作者
André J. Scheen
机构
[1] University of Liege,Division of Clinical Pharmacology and Division of Diabetes, Nutrition and Metabolic Disorders, Department of Medicine, CHU Sart Tilman
[2] CHU Sart Tilman (B35),Department of Medicine
来源
Clinical Pharmacokinetics | 2010年 / 49卷
关键词
Metformin; Digoxin; Simvastatin; Pioglitazone; Sulfonylurea;
D O I
暂无
中图分类号
学科分类号
摘要
Patients with type 2 diabetes mellitus (T2DM) are generally treated with many pharmacological compounds and are exposed to a high risk of drug-drug interactions. Indeed, blood glucose control usually requires acombination of various glucose-lowering agents, and the recommended global approachto reduce overall cardiovascular risk generally implies administration of several protective compounds, including HMG-CoA reductase inhibitors (statins), antihypertensive compounds and antiplatelet agents.
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页码:573 / 588
页数:15
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