Atherosclerosis and endothelial dysfunction in patients with ankylosing spondylitis

被引:0
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作者
V. F. Azevedo
R. Pecoits-Filho
机构
[1] Federal University of Paraná,Head of Spondylarthropathies Service
[2] Pontificia Universidade Catolica do Parana,Graduate Program in Health Sciences
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关键词
Spondylarthropathies; Ankylosing Spondylitis; Inflammation; Biomarkers; Cardiovascular disease; Atherosclerosis; Endothelial activation; Endothelial dysfunction; Arterial stiffness;
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摘要
Ankylosing spondylitis (AS) is a systemic inflammatory rheumatic disease characterized primarily by axial joint involvement, sacroiliitis and various extra-articular manifestations. High cardiovascular mortality in AS has led many researchers to investigate possible risk factors involved with cardiovascular disease in these patients. This review summarizes published data concerning endothelial dysfunction and atherosclerosis in patients with AS. The author discusses current limitations and problems related to a better assessment of these two possible changes in AS.
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页码:1411 / 1416
页数:5
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