Hypoferremia of infection: a double-edged sword?

被引：0
|
作者：
Kristen L Lokken
Renée M Tsolis
Andreas J Bäumler
机构：
[1] School of Medicine,Department of Medical Microbiology and Immunology
[2] University of California–Davis,undefined
来源：
Nature Medicine | 2014年 / 20卷
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摘要：
Pharmacologic modulation of iron metabolism may be a potential strategy to control infection caused by the intracellular bacteria Salmonella enterica var. Typhimurium (S. typhimurium) (pages 419–424). The molecular mechanism involves the estrogen-related receptor γ (ERRγ) in the liver, which can be targeted with an inverse agonist to improve survival of infected animals.
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页码：335 / 337
页数：2
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