Antioxidant Potential and In Situ Analysis of Major and Trace Element Determination of Ood-saleeb, a Known Unani Herbal Medicine by ICP-MS

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作者
Mohammad Raish
Ajaz Ahmad
Khalid M. Alkharfy
Fahad I. Al-Jenoobi
Abdullah M. Al-Mohizea
Kazi Mohsin
Syed Rizwan Ahamad
Naushad Ali
Faiyaz Shakeel
机构
[1] King Saud University,Department of Pharmaceutics, College of Pharmacy
[2] King Saud University,Department of Clinical Pharmacy, College of Pharmacy
[3] King Saud University,Research Centre, College of Pharmacy
[4] King Saud University,Quality Assurance Unit, College of Pharmacy
[5] King Saud University,Center of Excellence in Biotechnology Research (CEBR)
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Antioxidant; Ascorbic acid; Ood-saleeb; Trace elements; ICP-MS;
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摘要
The intention of the present research work was to investigate the antioxidant activity and trace element analysis of Ood-saleeb, a known herbal medicine. Preliminary screening of phytochemicals showed that the extract of Ood-saleeb had flavonoids and phenolics. The significant activities in all antioxidant assays were observed in the extract of Ood-saleeb in comparison with the standard antioxidant with respect to dose of Ood-saleeb. Incredible activities to scavenge reactive oxygen species were also observed by the extract of Ood-saleeb. The IC50 values of all factors were determined using ascorbic acid as a standard. The inductive coupled plasma-mass spectroscopy (ICP-MS) was employed for the estimation of trace elements in Ood-saleeb extract. The concentrations of up to 18 elements were detected successfully. Silicon was found in high concentration (85.3 μg/g) while lithium was in low concentration (3 ng/g). The trace elements in the sample were found at different percentage levels which play a key role in the treatment of diseases.
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页码:521 / 527
页数:6
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