Synthesis of (aryl/heteroaryl)-(6-(aryl/heteroaryl)pyridin-3-yl)methanones

被引：0
|
作者：
Dinesh Addla
Srinivas Kantevari
机构：
[1] CSIR-Indian Institute of Chemical Technology,Crop Protection Chemicals Division, (Organic Chemistry Division
来源：
Research on Chemical Intermediates | 2015年 / 41卷
关键词：
Condensation; β-Enaminones; Pyridine; Cerium chloride; Michael addition; Cyclodehydration;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
One-pot condensation of aryl/heteroaryl β-enaminones and ammonium acetate in the presence of CeCl3·7H2O–NaI led to the formation of novel (aryl/heteroaryl)(6-(aryl/heteroaryl)pyridin-3-yl)methanone in very good yields. Mechanistically, the reaction proceeds via tandem, regioselective Michael addition–cyclodehydration–elimination sequence.
引用
收藏
页码：3759 / 3765
页数：6
相关论文
共 50 条
  • [1] Synthesis of (aryl/heteroaryl)-(6-(aryl/heteroaryl)pyridin-3-yl)methanones
    Addla, Dinesh
    Kantevari, Srinivas
    RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (06) : 3759 - 3765
  • [2] Synthesis of α,α-Difluoroethyl Aryl and Heteroaryl Ethers
    Yang, Eddie
    Reese, Matthew R.
    Humphrey, John M.
    ORGANIC LETTERS, 2012, 14 (15) : 3944 - 3947
  • [3] Sustainable Synthesis of Aryl and Heteroaryl Aldehydes
    Paganelli, Stefano
    Tassini, Riccardo
    Piccolo, Oreste
    CHEMISTRYSELECT, 2022, 7 (28):
  • [4] Synthesis of 3-(6-aryl-pyridin-2-yl)- and 8-(6-aryl-pyridin-2-yl) coumarins
    Brahmbhatt, D. I.
    Gajera, J. M.
    Pandya, V. P.
    Patel, M. A.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2007, 46 (05): : 869 - 871
  • [5] Pd-Catalyzed Synthesis of Aryl and Heteroaryl Triflones from Reactions of Sodium Triflinate with Aryl (Heteroaryl) Triflates
    Smyth, Lynette A.
    Phillips, Eric M.
    Chan, Vincent S.
    Napolitano, Jose G.
    Henry, Rodger
    Shekhar, Shashank
    JOURNAL OF ORGANIC CHEMISTRY, 2016, 81 (03): : 1285 - 1294
  • [6] SYNTHESIS OF 3-VINYL-2-ARYL(HETEROARYL)INDOLES
    FERNANDEZ, I
    GALVEZ, C
    URPI, L
    ANALES DE QUIMICA, 1991, 87 (07): : 936 - 939
  • [7] Synthesis of 3-aryl- and 3-heteroaryl-7-azaindoles
    Alvarez, M
    Fernández, D
    Joule, JA
    SYNTHESIS-STUTTGART, 1999, (04): : 615 - 620
  • [8] SYNTHESIS OF 6-N-ARYL AND HETEROARYL BENZTHIAZOLES AS POTENTIAL ANTHELMINTICS
    ABUZAR, S
    SHARMA, S
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 1981, 36 (01): : 108 - 111
  • [9] Trideuteriomethoxylation of Aryl and Heteroaryl Halides
    Dash, Pragyanditi
    Janni, Manojkumar
    Peruncheralathan, S.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2012, 2012 (26) : 4914 - 4917
  • [10] Trifluoromethylation of aryl and heteroaryl halides
    Roy, Sudipta
    Gregg, Brian T.
    Gribble, Gordon W.
    Le, Van-Duc
    Roy, Sujata
    TETRAHEDRON, 2011, 67 (12) : 2161 - 2195
12345