Bone Formation;
Multiple Myeloma;
Mesenchymal Stem Cell;
Hematological Malignancy;
Bone Disease;
D O I:
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学科分类号:
摘要:
Multiple myeloma is a common hematological malignancy that leads to the occurrence of bone lesions. The combination of traditional cytotoxic and novel agents is usually taken to treat multiple myeloma-related bone diseases. However, the curative effect is not very satisfactory. Stem cell-based therapy has been recently introduced and investigated, which represents a new frontier in the treatment of multiple myeloma. In a recent interesting study, Dr Atsuta and colleagues provide a new insight into the effects of mesenchymal stem cells on multiple myeloma via Fas/Fas ligand pathway, which rekindles the fire of hope for those patients suffering from multiple myeloma.
机构:
Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol, Natl Clin Res Ctr Blood Dis, State Key Lab Expt Hematol, Tianjin 300020, Peoples R China
Chinese Acad Med Sci Peking Union Med Coll, Blood Dis Hosp, Tianjin 300020, Peoples R China
Tianjin Inst Hlth Sci, Tianjin 301600, Peoples R ChinaChinese Acad Med Sci & Peking Union Med Coll, Inst Hematol, Natl Clin Res Ctr Blood Dis, State Key Lab Expt Hematol, Tianjin 300020, Peoples R China
Xu, Jingyu
An, Gang
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机构:
Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol, Natl Clin Res Ctr Blood Dis, State Key Lab Expt Hematol, Tianjin 300020, Peoples R China
Chinese Acad Med Sci Peking Union Med Coll, Blood Dis Hosp, Tianjin 300020, Peoples R China
Tianjin Inst Hlth Sci, Tianjin 301600, Peoples R ChinaChinese Acad Med Sci & Peking Union Med Coll, Inst Hematol, Natl Clin Res Ctr Blood Dis, State Key Lab Expt Hematol, Tianjin 300020, Peoples R China
An, Gang
Qiu, Lugui
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机构:
Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol, Natl Clin Res Ctr Blood Dis, State Key Lab Expt Hematol, Tianjin 300020, Peoples R China
Chinese Acad Med Sci Peking Union Med Coll, Blood Dis Hosp, Tianjin 300020, Peoples R China
Tianjin Inst Hlth Sci, Tianjin 301600, Peoples R ChinaChinese Acad Med Sci & Peking Union Med Coll, Inst Hematol, Natl Clin Res Ctr Blood Dis, State Key Lab Expt Hematol, Tianjin 300020, Peoples R China
机构:
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Tianjin Institutes of HealthState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Jingyu Xu
Gang An
论文数: 0引用数: 0
h-index: 0
机构:
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Tianjin Institutes of HealthState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Gang An
Lugui Qiu
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h-index: 0
机构:
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Tianjin Institutes of HealthState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
机构:
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Tianjin Institutes of Health ScienceState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Jingyu Xu
Gang An
论文数: 0引用数: 0
h-index: 0
机构:
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Tianjin Institutes of Health ScienceState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Gang An
Lugui Qiu
论文数: 0引用数: 0
h-index: 0
机构:
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Tianjin Institutes of Health ScienceState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College
机构:
Med Coll Wisconsin, Div Hematol Oncol, Dept Med, Bone Marrow Transplant Program, Milwaukee, WI 53226 USAMed Coll Wisconsin, Div Hematol Oncol, Dept Med, Bone Marrow Transplant Program, Milwaukee, WI 53226 USA
Zaidi, AA
Vesole, DH
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h-index: 0
机构:
Med Coll Wisconsin, Div Hematol Oncol, Dept Med, Bone Marrow Transplant Program, Milwaukee, WI 53226 USAMed Coll Wisconsin, Div Hematol Oncol, Dept Med, Bone Marrow Transplant Program, Milwaukee, WI 53226 USA
机构:
Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Feinberg Sch Med, Div Hematol & Oncol,Multiple Myeloma Program, Chicago, IL 60611 USANorthwestern Univ, Robert H Lurie Comprehens Canc Ctr, Feinberg Sch Med, Div Hematol & Oncol,Multiple Myeloma Program, Chicago, IL 60611 USA
Singhal, S
BRITISH MEDICAL JOURNAL,
2003,
327
(7415):
: 575
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576