Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance

被引：0

作者：

Susana Minguet

Kathrin Kläsener

Anna-Maria Schaffer

Gina J Fiala

Teresa Osteso-Ibánez

Katrin Raute

Inmaculada Navarro-Lérida

Frederike A Hartl

Maximilian Seidl

Michael Reth

Miguel A Del Pozo

机构：

[1] Institute for Biology III,Department of Immunology

[2] Faculty of Biology,undefined

[3] University of Freiburg,undefined

[4] Centre for Biological Signalling Studies BIOSS,undefined

[5] University of Freiburg,undefined

[6] Center for Chronic Immunodeficiency (CCI),undefined

[7] University Medical Center Freiburg,undefined

[8] Faculty of Medicine,undefined

[9] University of Freiburg,undefined

[10] Mechanoadaptation & Caveolae Biology Lab,undefined

[11] Cell Biology & Physiology Program,undefined

[12] Cell & Developmental Biology Area,undefined

[13] Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC),undefined

[14] Max Planck Institute of Immunology and Epigenetics,undefined

[15] Spemann Graduate School for Biology and Medicine (SGBM),undefined

[16] University of Freiburg,undefined

[17] Institute for Surgical Pathology,undefined

[18] University Medical Center Freiburg,undefined

[19] University of Freiburg,undefined

来源：

Nature Immunology | 2017年 / 18卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Immature B cells are subject to tolerance mechanisms that prevent the expression of self-reactive BCRs. Minguet and colleagues identify the membrane protein caveolin-1 as a regulator of BCR spatial organization and signaling that enforces B cell tolerance.

引用

页码：1150 / 1159

页数：9

共 50 条

[1] Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance
Minguet, Susana
Klaesener, Kathrin
Schaffer, Anna-Maria
Fiala, Gina J.
Osteso-Ibanez, Teresa
Raute, Katrin
Navarro-Lerida, Inmaculada
Hartl, Frederike A.
Seidl, Maximilian
Reth, Michael
Del Pozo, Miguel A.
NATURE IMMUNOLOGY, 2017, 18 (10) : 1150 - +
[2] Caveolin-1-dependent and -independent membrane domains
Le Lay, Soazig
Li, Qiong
Proschogo, Nicholas
Rodriguez, Macarena
Gunaratnam, Krishanthi
Cartland, Sian
Rentero, Carles
Jessup, Wendy
Mitchell, Todd
Gaus, Katharina
JOURNAL OF LIPID RESEARCH, 2009, 50 (08) : 1609 - 1620
[3] Prometastatic NEDD9 Regulates Individual Cell Migration via Caveolin-1-Dependent Trafficking of Integrins
Kozyulina, Polina Y.
Loskutov, Yuriy V.
Kozyreva, Varvara K.
Rajulapati, Anuradha
Ice, Ryan J.
Jones, Brandon C.
Pugacheva, Elena N.
MOLECULAR CANCER RESEARCH, 2015, 13 (03) : 423 - 438
[4] Selective caveolin-1-dependent endocytosis of glycosphingolipids
Singh, RD
Puri, V
Valiyaveettil, JT
Marks, DL
Bittman, R
Pagano, RE
MOLECULAR BIOLOGY OF THE CELL, 2003, 14 (08) : 3254 - 3265
[5] Spreading depolarizations trigger caveolin-1-dependent endothelial transcytosis
Sadeghian, Homa
Lacoste, Baptiste
Qin, Tao
Toussay, Xavier
Rosa, Roberto
Oka, Fumiaki
Chung, David Y.
Takizawa, Tsubasa
Gu, Chenghua
Ayata, Cenk
ANNALS OF NEUROLOGY, 2018, 84 (03) : 409 - 423
[6] Caveolin-1-dependent apoptosis induced by fibrin degradation products
Guo, Yi-He
Hernandez, Irene
Isermann, Berend
Kang, Tae-bong
Medved, Leonid
Sood, Rashmi
Kerschen, Edward J.
Holyst, Trudy
Mosesson, Michael W.
Weiler, Hartmut
BLOOD, 2009, 113 (18) : 4431 - 4439
[7] Caveolin-1-dependent β1 integrin endocytosis is a critical regulator of fibronectin turnover
Shi, Feng
Sottile, Jane
JOURNAL OF CELL SCIENCE, 2008, 121 (14) : 2360 - 2371
[8] Fibronectin matrix turnover occurs through a caveolin-1-dependent process
Sottile, J
Chandler, J
MOLECULAR BIOLOGY OF THE CELL, 2005, 16 (02) : 757 - 768
[9] Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration
Ravid, Dona
Chuderland, Dana
Landsman, Limor
Lavie, Yaakov
Reich, Reuven
Liscovitch, Mordechai
EXPERIMENTAL CELL RESEARCH, 2008, 314 (15) : 2762 - 2773
[10] Pilus Phase Variation Switches Gonococcal Adherence to Invasion by Caveolin-1-Dependent Host Cell Signaling
Faulstich, Michaela
Boettcher, Jan-Peter
Meyer, Thomas F.
Fraunholz, Martin
Rudel, Thomas
PLOS PATHOGENS, 2013, 9 (05):

← 1 2 3 4 5 →