SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control

被引：0
|
作者：
Shuying Sun
Zuo Zhang
Rahul Sinha
Rotem Karni
Adrian R Krainer
机构：
[1] Cold Spring Harbor Laboratory,Department of Biochemistry and Molecular Biology
[2] Graduate Program in Molecular and Cellular Biology,undefined
[3] Stony Brook University,undefined
[4] Merck Research Laboratories,undefined
[5] Merck & Co.,undefined
[6] Inc.,undefined
[7] The Hebrew University Medical School,undefined
[8] Ein Karem,undefined
来源：
Nature Structural & Molecular Biology | 2010年 / 17卷
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学科分类号：
摘要：
SF2/ASF is a key splicing factor and is abnormally overexpressed in some tumors. By examining the post-transcriptional regulation of this factor, it is now found that SF2/ASF downregulates its own expression through multiple mechanisms.
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页码：306 / 312
页数：6
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