The Pharmacokinetics of Fondaparinux Sodium in Healthy Volunteers

被引：0
|
作者：
François Donat
Jean Pierre Duret
Alix Santoni
Roger Cariou
José Necciari
Harry Magnani
Rik de Greef
机构：
[1] Sanofi-Synthelabo Groupe,
[2] Organon,undefined
来源：
Clinical Pharmacokinetics | 2002年 / 41卷
关键词：
Venous Thromboembolism; Fondaparinux; Elderly Volunteer; Young Volunteer; Subcutaneous Dose;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objective: Fondaparinux sodium is the first in a new class of synthetic factor Xa inhibitors that binds reversibly with high affinity to antithrombin III. It has been investigated for the prevention and treatment of arterial and venous thrombotic disorders and approved for use at a dose of 2.5mg once daily in the prevention of venous thromboembolism in major orthopaedic surgery. The pharmacokinetics of fondaparinux sodium were determined in eight studies in young and elderly healthy volunteers.
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页码：1 / 9
页数：8
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