The effect of sample storage on the Peroxidation of Leukocytes Index Ratio (PLIR) measure

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作者
Ilaria Peluso
Husseen Manafikhi
Fabio Altieri
Christian Zanza
Maura Palmery
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[1] “Sapienza” University of Rome,Department of Physiology and Pharmacology “V. Erspamer”
[2] “Sapienza” University of Rome,Department of Biochemical Sciences “Alessandro Rossi Fanelli”
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Scientific Reports | / 4卷
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摘要
Delays in processing are frequent because of problems associated with transporting the samples to the laboratory. Thus, we aimed to evaluate the effect of sample storage on the Peroxidation of Leukocytes Index Ratio (PLIR). Differences between PLIR values of lymphocytes (PLIR-L), monocytes (PLIR-M) and granulocytes (PLIR-G) were observed in fresh samples. Sample storage affected the evaluation of PLIR. In particular, PLIR-L was lower in stored samples compared to fresh samples. In conclusion, our results suggest that fresh samples are recommended for assessing the PLIR.
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