CNS-associated macrophages shape the inflammatory response in a mouse model of Parkinson’s disease

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作者：
Maximilian Frosch
Lukas Amann
Marco Prinz
机构：
[1] University of Freiburg,Faculty of Medicine, Institute of Neuropathology
[2] University of Freiburg,Signalling Research Centres BIOSS and CIBSS
来源：
Nature Communications | / 14卷
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摘要：
In an alpha-synuclein (α-syn) model of Parkinson’s disease (PD), Schonhoff and colleagues have shown that central nervous system (CNS)-associated macrophages (CAMs), but not microglia, potentially orchestrate CD4+ T cell recruitment and mediate an α-syn-induced inflammatory makeup.
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