TopiramateAs Monotherapy in Newly Diagnosed Epilepsy

被引：0
|
作者：
John Waugh
Karen L. Goa
机构：
[1] Adis International Limited,
来源：
CNS Drugs | 2003年 / 17卷
关键词：
Carbamazepine; Valproate; Topiramate; Zonisamide; Clonic Seizure;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
▴ Topiramate is an antiepileptic drug that has a broad spectrum of antiseizure effects, which appear to be the result of several neurostabilising pharmacological mechanisms. These include blockade of ion channels, potentiation of GABA neuroinhibition and glutamate receptor antagonism at non-NMDA receptors, as well as mild inhibition of carbonic anhydrase.
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页码：985 / 992
页数：7
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