Epstein-Barr virus lytic gene expression is tightly linked to ER stress but not cytotoxicity with bortezomib or nelfinavir

被引:0
|
作者
Courtney M Shirley
Nene Kalu
Meir Shamay
Richard F Ambinder
机构
[1] Johns Hopkins University School of Medicine,Department of Oncology
关键词
Bortezomib; Unfold Protein Response; Nelfinavir; Unfold Protein Response Activation; Proteasome Inhibitor Bortezomib;
D O I
10.1186/1750-9378-7-S1-P32
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Arsenicals, the Integrated Stress Response, and Epstein-Barr Virus Lytic Gene Expression
    Lee, Jaeyeun
    Stone, Jennifer
    Desai, Prashant
    Kosowicz, John G.
    Liu, Jun O.
    Ambinder, Richard F.
    VIRUSES-BASEL, 2021, 13 (05):
  • [2] Epstein-Barr Virus and Kaposi's Sarcoma Herpesvirus Lytic Cycle Induction with Bortezomib Is a Response to ER Stress
    O'Farrell, Courtney
    Shamay, Meir
    Kalu, Nene
    DuFresne, Andrew
    Biswas, Sunetra
    Ambinder, Richard F.
    BLOOD, 2010, 116 (21) : 726 - 726
  • [3] Analysis of Epstein-Barr virus and cellular gene expression during the early phases of Epstein-Barr virus lytic induction
    Auburn, Helen
    Zuckerman, Mark
    Smith, Melvyn
    JOURNAL OF MEDICAL MICROBIOLOGY, 2016, 65 : 1243 - 1252
  • [4] Bortezomib-induced Epstein-Barr virus and Kaposi sarcoma herpesvirus lytic gene expression: oncolytic strategies
    Reid, Erin G.
    CURRENT OPINION IN ONCOLOGY, 2011, 23 (05) : 482 - 487
  • [5] Lytic cycle gene regulation of Epstein-Barr virus
    Amon, W
    Binné, UK
    Bryant, H
    Jenkins, PJ
    Karstegl, CE
    Farrell, PJ
    JOURNAL OF VIROLOGY, 2004, 78 (24) : 13460 - 13469
  • [6] Latent and Lytic Epstein-Barr Virus Gene Expression in the Peripheral Blood of Astronauts
    Stowe, Raymond P.
    Kozlova, Elena V.
    Sams, Clarence F.
    Pierson, Duane L.
    Walling, Dennis M.
    JOURNAL OF MEDICAL VIROLOGY, 2011, 83 (06) : 1071 - 1077
  • [7] Lytic replication of Epstein-Barr virus
    Lu, Chih-Chung
    Chen, Mei-Ru
    FUTURE VIROLOGY, 2006, 1 (04) : 435 - 446
  • [8] Bortezomib induction of the unfolded protein response mediates Epstein-Barr virus lytic activation but is separable from bortezomib-induced cytotoxicity
    Shirley, Courtney
    Kalu, Nene
    Shamay, Meir
    Ambinder, Richard F.
    CANCER RESEARCH, 2012, 72
  • [9] Pharmacologic Activation of Lytic Epstein-Barr Virus Gene Expression without Virion Production
    Lee, Jaeyeun
    Kosowicz, John G.
    Hayward, S. Diane
    Desai, Prashant
    Stone, Jennifer
    Lee, Jae Myun
    Liu, Jun O.
    Ambinder, Richard F.
    JOURNAL OF VIROLOGY, 2019, 93 (20)
  • [10] ASPIRIN INDUCES LYTIC CYTOTOXICITY IN EPSTEIN-BARR VIRUS-POSITIVE CELLS
    Liu, Su Fang
    Wang, Hai
    Li, Zi Jian
    Deng, Xi Yun
    Xiang, Hui
    Tao, Yong Guang
    Li, Wei
    Tang, Min
    Cao, Ya
    CELL BIOLOGY INTERNATIONAL, 2008, 32 (03) : S32 - S32