Synthesis and study of the reactions of 2,5- and 1,2,5-substituted 6-aminoindoles

被引：0
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作者：
S. A. Yamashkin
N. N. Artaeva
E. A. Alyamkina
机构：
[1] M. E. Evsevʼev Mordovian State Pedagogical Institute,
来源：
Chemistry of Heterocyclic Compounds | 2010年 / 46卷
关键词：
acetylacetone; dibenzoylmethane; 2,5-dimethyl- and 5-methyl-2-phenylindoles; 2,5-dimethyl-; 1,2,5-trimethyl-; 5-methyl-2-phenyl; 1,5-dimethyl-2-phenyl-6-nitro- and 6-aminoindoles;
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摘要：
It has been shown that nitration with a KNO3 + H2SO4 mixture of 2,5-dimethyl- and 5-methyl-2-phenylindoles proceeds strictly selectively with the formation of 6-nitro derivatives, by reduction of which the corresponding aminoindoles were synthesized. It was established that the condensation of the aminoindoles obtained with β-diketones leads initially to enamino ketones, which in the presence of various acidic reagents are not subject to cyclization, i.e. may not be used for the synthesis of the corresponding pyrroloquinolines.
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页码：419 / 425
页数：6
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