Hypoxia May Increase Rat Insulin mRNA Levels by Promoting Binding of the Polypyrimidine Tract-binding Protein (PTB) to the Pyrimidine-rich Insulin mRNA 3′-Untranslated Region

被引：0

作者：

Linda Tillmar

Nils Welsh

机构：

[1] Uppsala University,Department of Medical Cell Biology

[2] Biomedicum,undefined

来源：

Molecular Medicine | 2002年 / 8卷

关键词：

Insulin mRNA; Polypyrimidine Tract-binding Protein; Reporter Gene mRNA; Pyrimidine-rich Sequences; Islets;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：263 / 272

页数：9

共 47 条

[1] Hypoxia may increase rat insulin mRNA levels by promoting binding of the polypyrimidine tract-binding protein (PTB) to the pyrimidine-rich insulin mRNA 3′-untranslated region
Tillmar, L
Welsh, N
[J]. MOLECULAR MEDICINE, 2002, 8 (05) : 263 - 272
[2] Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3′-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin
Tillmar, L
Welsh, N
[J]. MOLECULAR AND CELLULAR BIOCHEMISTRY, 2004, 260 (1-2) : 85 - 90
[3] Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3′-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin
Linda Tillmar
Nils Welsh
[J]. Molecular and Cellular Biochemistry, 2004, 260 : 85 - 90
[4] Characterization of the hypoxia-inducible protein binding site within the pyrimidine-rich tract in the 3'-untranslated region of the tyrosine hydroxylase mRNA
CzyzykKrzeska, MF
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[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (06) : 3293 - 3299
[5] Hypoxia increases insulin mRNA levels by stimulating binding of a protein to a hypoxia element in rat insulin mRNA
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[6] Regulation of tyrosine hydroxylase mRNA stability by protein-binding, pyrimidine-rich sequence in the 3′-untranslated region
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Czyzyk-Krzeska, MF
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (04) : 2532 - 2538
[7] Control of insulin mRNA stability in rat pancreatic islets -: Regulatory role of a 3′-untranslated region pyrimidine-rich sequence
Tillmar, L
Carlsson, C
Welsh, N
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (02) : 1099 - 1106
[8] Increased expression of polypyrimidine tract binding protein results in higher insulin mRNA levels
Fred, RG
Welsh, N
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005, 328 (01) : 38 - 42
[9] hnRNP C and polypyrimidine tract-binding protein specifically interact with the pyrimidine-rich region within the 3′NTR of the HCV RNA genome
Gontarek, RR
Gutshall, LL
Herold, KM
Tsai, J
Sathe, GM
Mao, J
Prescott, C
Del Vecchio, AM
[J]. NUCLEIC ACIDS RESEARCH, 1999, 27 (06) : 1457 - 1463
[10] The poly(C) binding protein may bind to and increase insulin mRNA levels in rat islets
Tillmar, L
Welsh, N
[J]. DIABETOLOGIA, 2000, 43 : A119 - A119

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