National, sub-national, and risk-attributed burden of thyroid cancer in Iran from 1990 to 2019

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作者
Mohammadreza Azangou-Khyavy
Sahar Saeedi Moghaddam
Negar Rezaei
Zahra Esfahani
Nazila Rezaei
Sina Azadnajafabad
Mohammad-Mahdi Rashidi
Esmaeil Mohammadi
Seyed Mohammad Tavangar
Hamidreza Jamshidi
Ali H. Mokdad
Mohsen Naghavi
Farshad Farzadfar
Bagher Larijani
机构
[1] Tehran University of Medical Sciences,Non
[2] Tehran University of Medical Sciences,Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute
[3] Tehran University of Medical Sciences,Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute
[4] Shahid Beheshti University of Medical Sciences,Department of Pathology, Shariati Hospital
[5] University of Washington,Department of Pharmacology, School of Medicine
[6] University of Washington,Department of Health Metrics Sciences, School of Medicine
[7] Tehran University of Medical Sciences,Institute for Health Metrics and Evaluation
[8] Karolinska University Hospital,Research Center for Immunodeficiencies
[9] Shahid Beheshti University of Medical Sciences,Department of Biosciences and Nutrition
[10] Shahrekord University of Medical Sciences,School of Advanced Technologies in Medicine
[11] Shahid Beheshti University of Medical Sciences,Department of Epidemiology and Biostatistics
[12] Khomein University of Medical Sciences,Department of Epidemiology
[13] Golestan University of Medical Sciences,Department of Health Services Management
[14] Iran University of Medical Sciences,Neuroscience Research Center
[15] Iran University of Medical Sciences,Department of Internal Medicine
[16] Zanjan University of Medical Sciences,Health Management and Economics Research Center
[17] Shahroud University of Medical Sciences,Department of Immunology
[18] Golestan University of Medical Sciences,School of Medicine
[19] Babol University of Medical Sciences,Golestan Research Center of Gastroentrology and Hepatology
[20] Mazandaran University of Medical Sciences,Social Determinants of Health Research Center
[21] Maastricht University,Toxoplasmosis Research Center
[22] Shiraz University of Medical Sciences,Department of Epidemiology
[23] Arak University of Medical Sciences,Department of Epidemiology
[24] Isfahan University of Medical Sciences,Department of Parasitology and Mycology
[25] Qazvin University of Medical Sciences,Department of Environmental Health Engineering
[26] Sana Institute of Higher Education,School of Public Health
[27] Arak University of Medical Sciences,Department of Genetics
[28] Johns Hopkins University,Department of Nursing
[29] Tehran University of Medical Sciences,Department of Radiology and Radiological Science
[30] Shahid Beheshti University of Medical Sciences,School of Medicine
[31] Shahid Beheshti University of Medical Sciences,Department of Pharmacology
[32] Guilan University of Medical Sciences,Obesity Research Center
[33] Guilan University of Medical Sciences,Gastrointestinal and Liver Diseases Research Center
[34] Iran University of Medical Sciences,Caspian Digestive Disease Research Center
[35] Mashhad University of Medical Sciences,Minimally Invasive Surgery Research Center
[36] Baku State University,Department of Biophysics and Biochemistry
[37] Moscow State Pedagogical University,Russian Institute for Advanced Study
[38] Shahid Beheshti University of Medical Sciences,Department of Health & Community Medicine
[39] The Iranian Academy of Medical Sciences,Social Determinants of Health Research Center
[40] Shahid Beheshti University of Medical Sciences,Children’s Medical Center
[41] Shahid Beheshti University of Medical Sciences,Social Determinants of Health Research Center
[42] Tehran University of Medical Sciences,Radiology Department
[43] Saveh University of Medical Sciences,Cellular and Molecular Biology Research Center, Health Research Institute
[44] Golestan University of Medical Sciences,Department of Clinical Biochemistry
[45] Babol University of Medical Sciences,Department of Community Medicine
[46] Babol University of Medical Sciences,Substance Abuse Prevention Research Center
[47] Shahid Beheshti University of Medical Sciences,Tehran Heart Center
[48] Kermanshah University of Medical Sciences,Department of Nursing
[49] Tehran University of Medical Sciences,Department of Physiology
[50] Mashhad University of Medical Sciences,Department of Pediatrics
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摘要
An updated exploration of the burden of thyroid cancer across a country is always required for making correct decisions. The objective of this study is to present the thyroid cancer burden and attributed burden to the high Body Mass Index (BMI) in Iran at national and sub-national levels from 1990 to 2019. The data was obtained from the GBD 2019 study estimates. To explain the pattern of changes in incidence from 1990 to 2019, decomposition analysis was conducted. Besides, the attribution of high BMI in the thyroid cancer DALYs and deaths were obtained. The age-standardized incidence rate of thyroid cancer was 1.57 (95% UI: 1.33–1.86) in 1990 and increased 131% (53–191) until 2019. The age-standardized prevalence rate of thyroid cancer was 30.19 (18.75–34.55) in 2019 which increased 164% (77–246) from 11.44 (9.38–13.85) in 1990. In 2019, the death rate, and Disability-adjusted life years of thyroid cancer was 0.49 (0.36–0.53), and 13.16 (8.93–14.62), respectively. These numbers also increased since 1990. The DALYs and deaths attributable to high BMI was 1.91 (0.95–3.11) and 0.07 (0.04–0.11), respectively. The thyroid cancer burden and high BMI attributed burden has increased from 1990 to 2019 in Iran. This study and similar studies’ results can be used for accurate resource allocation for efficient management and all potential risks’ modification for thyroid cancer with a cost-conscious view.
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