Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography

被引：0
|
作者：
Weili Pan
Hui Dong
Rong Sun
Linlin Zhao
Meng Sun
Longyan Li
Xianghao Yu
Jinxin Liu
Jianjun Wu
Fan Yang
Bo Yu
机构：
[1] The Second Affiliated Hospital of Harbin Medical University,Department of Cardiology
[2] Chinese Ministry of Education,The Key Laboratory of Myocardial Ischemia
[3] People’s Liberation Army Joint Logistics Support Unit 962 Hospital,Department of Cardiology
来源：
Journal of Cardiovascular Translational Research | 2021年 / 14卷
关键词：
Plasma ceramides; Plaque vulnerability; STEMI;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Plasma ceramides (Cer), a subset of bioactive lipids, have mechanistic links to development of atherosclerosis and are related to major adverse cardiovascular events (MACEs). Previous researches have demonstrated vulnerable plaques contribute to acute cardiovascular events and poor prognosis. This study aimed to explore the associations between Cer and culprit plaque characterizations evaluated by optical coherence tomography (OCT). It was found that plasma Cer are associated with culprit plaque vulnerability evaluated by OCT, providing evidence supporting proatherogenic roles and potential to act as markers for plaque vulnerability of Cer.
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页码：140 / 149
页数：9
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