New Insights on Biomarkers in Systemic Vasculitis

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作者
Rodolfo Perez-Alamino
Hernán Maldonado-Ficco
机构
[1] Hospital Nicolás Avellaneda,Rheumatology Section
[2] Clínica Regional Del Sud,Rheumatology
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关键词
Biomarkers; Systemic vasculitis; ANCA-associated vasculitis; B and T cells; Giant cell arteritis; Takayasu arteritis; Polyarteritis nodosa; Kawasaki disease; Cogan syndrome; Prognosis; Therapy;
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摘要
The systemic vasculitis is a heterogeneous group of diseases characterized by the inflammation of blood vessels. The development of advanced diagnostic tests and genetic studies have resulted in greater improvement in our understanding of vasculitis pathogenesis and thus in the development of newer therapies. However, there is still an unmet need in the management of systemic vasculitis, focused on developing of new biomarkers that would enable distinction between active disease from damage or infection and predict treatment response and prognosis.
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