The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

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作者
Miten Jain
Hugh E. Olsen
Benedict Paten
Mark Akeson
机构
[1] University of California,UC Santa Cruz Genomics Institute and Department of Biomolecular Engineering
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International Space Station; Read Accuracy; Rolling Circle Amplification; Next Generation Sequencing Platform; Hierarchical Dirichlet Process;
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摘要
Nanopore DNA strand sequencing has emerged as a competitive, portable technology. Reads exceeding 150 kilobases have been achieved, as have in-field detection and analysis of clinical pathogens. We summarize key technical features of the Oxford Nanopore MinION, the dominant platform currently available. We then discuss pioneering applications executed by the genomics community.
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