Preoperative Radiation with Concurrent 5-Fluorouracil for Locally Advanced T4-Primary Rectal Cancer

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作者
Claus Rödel
Gerhard G. Grabenbauer
Christoph Schick
Thomas Papadopoulos
Werner Hohenberger
Rolf Sauer
机构
[1] Department of Radiation Oncology,
[2] University of Erlangen,undefined
[3] Germany,undefined
[4] Department of Surgery,undefined
[5] University of Erlangen,undefined
[6] Germany ,undefined
[7] Institute of Pathology,undefined
[8] University of Erlangen,undefined
[9] Germany,undefined
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关键词
Key Words: cT4-rectal cancer; Preoperative radiochemotherapy; Schlüsselwörter: cT4-Rektumkarzinom; Präoperative Radiochemotherapie;
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摘要
In cT4-rectal carcinoma disease-free margins often cannot be obtained by primary surgery, and even if total en bloc resection is accomplished, local failure remains high with surgery alone. Herein we report on the curative resectability rate, acute toxicities, surgical complications, local control and 5-year survival rates achieved with a more aggressive multimodality regimen, including preoperative radiochemotherapy.
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页码:161 / 167
页数:6
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