Neutrophil-derived serine proteases in immune complex-mediated diseases

被引:0
|
作者
Sofia Z. Raptis
Christine T. N. Pham
机构
[1] Washington University School of Medicine,
来源
Immunologic Research | 2005年 / 32卷
关键词
Serine proteases; Cathepsin G; Neutrophil elastase; Neutrophils; Inflammation;
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学科分类号
摘要
Neutrophil-derived serine proteases play an important role in fighting infections. However, emerging data suggest that these proteases also regulate noninfectious inflammatory responses. Loss-of-function mutations in serine proteases have provided critical insights into the significance of these serine proteases in initiating and amplifying immune complex-mediated diseases.
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页码:211 / 215
页数:4
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