Benefit of Filgotinib, a JAK1 Preferential Inhibitor, in Rheumatoid Arthritis Patients with Previous Rapid Radiographic Progression: Post Hoc Analysis of Two Trials

被引:0
|
作者
Yoshiya Tanaka
Tatsuya Atsumi
Daniel Aletaha
Beatrix Bartok
Alena Pechonkina
Ling Han
Kahaku Emoto
Shungo Kano
Vijay Rajendran
Tsutomu Takeuchi
机构
[1] University of Occupational and Environmental Health,The First Department of Internal Medicine, School of Medicine
[2] Japan,Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine
[3] Hokkaido University,Division of Rheumatology, Department of Internal Medicine
[4] Medical University of Vienna,undefined
[5] Gilead Sciences,undefined
[6] Inc.,undefined
[7] Gilead Sciences K.K.,undefined
[8] Galapagos NV,undefined
[9] Keio University School of Medicine,undefined
[10] Saitama Medical University,undefined
来源
Rheumatology and Therapy | 2023年 / 10卷
关键词
Filgotinib; Adalimumab; Methotrexate; Rheumatoid arthritis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:161 / 185
页数:24
相关论文
共 50 条
  • [1] Benefit of Filgotinib, a JAK1 Preferential Inhibitor, in Rheumatoid Arthritis Patients with Previous Rapid Radiographic Progression: Post Hoc Analysis of Two Trials
    Tanaka, Yoshiya
    Atsumi, Tatsuya
    Aletaha, Daniel
    Bartok, Beatrix
    Pechonkina, Alena
    Han, Ling
    Emoto, Kahaku
    Kano, Shungo
    Rajendran, Vijay
    Takeuchi, Tsutomu
    [J]. RHEUMATOLOGY AND THERAPY, 2023, 10 (01) : 161 - 185
  • [2] Filgotinib, a JAK1 Inhibitor, for Treatment-Resistant Rheumatoid Arthritis
    Singh, Jasvinder A.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2019, 322 (04): : 309 - 311
  • [3] RADIOGRAPHIC CHANGE IN PATIENTS WITH RHEUMATOID ARTHRITIS AND ESTIMATED BASELINE YEARLY PROGRESSION ≥5 OR <5: POST HOC ANALYSIS OF TWO PHASE 3 TRIALS OF FILGOTINIB
    Tanaka, Y.
    Atsumi, T.
    Aletaha, D.
    Landewe, R. B. M.
    Bartok, B.
    Pechonkina, A.
    Yin, Z.
    Han, L.
    Emoto, K.
    Kano, S.
    Rajendran, V.
    Takeuchi, T.
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2022, 81 : 604 - 605
  • [4] Radiographic Change in Patients with Rheumatoid Arthritis and Estimated Baseline Yearly Progression ≥5 or <5: Post Hoc Analysis of Two Phase 3 Trials of Filgotinib
    Tanaka, Yoshiya
    Atsumi, Tatsuya
    Aletaha, Daniel
    Landewe, Robert
    Bartok, Beatrix
    Pechonkina, Alena
    Han, Ling
    Emoto, Kahaku
    Kano, Shungo
    Rajendran, Vijay
    Takeuchi, Tsutomu
    [J]. ARTHRITIS & RHEUMATOLOGY, 2022, 74 : 581 - 584
  • [5] Filgotinib, a novel JAK1-preferential inhibitor for the treatment of rheumatoid arthritis: An overview from clinical trials
    Tanaka, Yoshiya
    Kavanaugh, Arthur
    Wicklund, Jason
    McInnes, Iain B.
    [J]. MODERN RHEUMATOLOGY, 2022, 32 (01) : 1 - 11
  • [6] FILGOTINIB, AN ORAL JAK1 SELECTIVE INHIBITOR WITH A RAPID ONSET OF ACTION: RESULTS FROM THE DARWIN 1 STUDY IN METHOTREXATE INADEQUATE RESPONSE RHEUMATOID ARTHRITIS PATIENTS
    Taylor, Peter C.
    Westhovens, Rene
    Vyncke, Veerle
    Meuleners, Luc
    Van der Aa, Annegret
    Harrison, Pille
    Tasset, Chantal
    [J]. RHEUMATOLOGY, 2017, 56 : 27 - 27
  • [7] FILGOTINIB, A SELECTIVE JANUS KINASE 1 (JAK1) INHIBITOR, MODULATES DISEASE-ASSOCIATED CYTOKINES IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS
    Taylor, Peter C.
    Elboudwarej, Emon
    LI Wanying
    Hawtin, Rachael E.
    Liu, Jinfeng
    Mirza, Amer M.
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2019, 78 : 736 - 736
  • [8] Filgotinib, a JAK1 Inhibitor, Modulates Disease-Related Biomarkers in Rheumatoid Arthritis: Results from Two Randomized, Controlled Phase 2b Trials
    Jacqueline M. Tarrant
    René Galien
    Wanying Li
    Lovely Goyal
    Yang Pan
    Rachael Hawtin
    Wangshu Zhang
    Annegret Van der Aa
    Peter C. Taylor
    [J]. Rheumatology and Therapy, 2020, 7 : 173 - 190
  • [9] Filgotinib, a JAK1 Inhibitor, Modulates Disease-Related Biomarkers in Rheumatoid Arthritis: Results from Two Randomized, Controlled Phase 2b Trials
    Tarrant, Jacqueline M.
    Galien, Rene
    Li, Wanying
    Goyal, Lovely
    Pan, Yang
    Hawtin, Rachael
    Zhang, Wangshu
    Van der Aa, Annegret
    Taylor, Peter C.
    [J]. RHEUMATOLOGY AND THERAPY, 2020, 7 (01) : 173 - 190
  • [10] Efficacy of Filgotinib in Patients with Rheumatoid Arthritis with Poor Prognostic Factors: Post Hoc Analysis
    Aletaha, Daniel
    Westhovens, Rene
    Gaujoux-Viala, Cecile
    Adami, Giovanni
    Matsumoto, Alan
    Bird, Paul
    Messina, Osvaldo Daniel
    Buch, Maya
    Bartok, Beatrix
    Yin, Zhaoyu
    Guo, Ying
    Hendrikx, Thijs
    Burmester, Gerd
    [J]. ARTHRITIS & RHEUMATOLOGY, 2020, 72